49ers WR Deebo Samuel Out: Survivor-Pick Read on SF
Oct 12, 2026
Deebo Samuel exits with a hamstring injury
Deebo Samuel is out for San Francisco after hurting his hamstring on a running play Sunday. Hamstring injuries for a player used as heavily on the ground as Samuel are worth watching closely, since they tend to linger and can quietly sap a player's availability for weeks.
What it means for your survivor pick
The good news for anyone eyeing the 49ers: the schedule stays favorable. San Francisco is a 5.5-point home favorite against Washington in Week 6, then a 4.5-point favorite at Atlanta in Week 7. Those are the kinds of spreads survivor players look for, and losing a wideout — even one as versatile as Samuel — doesn't torpedo a mid-single-digit favorite on its own.
That said, treat SF as a solid-but-not-slam-dunk option rather than a lock. A 5.5-point favorite is comfortable but far from bulletproof, and the offense losing a playmaker nudges the margin of error in the wrong direction. If you've already burned San Francisco earlier in the season, the Week 6 and Week 7 slates almost certainly offer bigger favorites worth checking first. Weigh it against the rest of the board before you commit — you can compare the week's options and lock your survivor pick once you've seen the full slate.
New to the format or running a league of your own? Here's how to start a free survivor pool and get your picks in before kickoff.